Power efficient and compact, the AMD Radeon Pro WX 2100 is a low-profile professional workstation graphics card that features 512 stream processors coupled to 2GB of GDDR5 vRAM with a 48 GB/s memory interface for 1.25 TFLOPS of single-precision computation performance, all packed inside a half-height, half-length form factor. This speed coupled with the small size ensures that smaller workstations can take advantage of APIs such as OpenCL, OpenGL, and Vulkan. Using the included full-height bracket, this card can fit into standard workstation form-factor PCs as well.

The output panel of this card contains two Mini DisplayPort outputs and a single full-sized DisplayPort output. With the included Mini DisplayPort to DVI adapter, legacy hardware is also supported. With the processing power available inside the WX 2100 card, a single 5K (5120x2880) display, or two DCI or UHD 4K displays can be driven without requiring secondary cards or MST hubs.

To keep this card cool, AMD implemented a blower-style cooler. By using a radial fan, this system forces air over the components and exhausts it out through the front of the card. This compact cooling solution is ideal for configurations involving tight spacing between components, crucial in small-form-factor enclosures.